Acetaminophen and Ethinyl Estradiol/Norethindrone

Effects and Recommendation :
Acetaminophen may increase blood levels of Ethinyl Estradiol/Norethindrone. Ethinyl Estradiol/Norethindrone may reduce or delay the effects of Acetaminophen.
Not clinically significant. No adjustments appear to be necessary.
Severity of the interaction : 1/6

Information on this interaction is found in the following publications :
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Back DJ, Orme ML. "Pharmacokinetic drug interactions with oral contraceptives." Clin Pharmacokinet. 1990 June;18: 472-84.
Publication : Clin Pharmacokinet by
> Back DJ, Orme ML - Pharmacokinetic drug interactions with oral contra - 472-84
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Minors JO, Hawood J, Birkett DJ. "Influence of sex and oral contraceptive steroids on paracetamol metabolism." Br J Clin Pharmacol. 1983 Nov;16: 503-9.
Publication : Br J Clin Pharmacol by
> Minors JO, Hawood J, Birkett DJ - Influence of sex and oral contraceptive steroids o - 503-9
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Shenfield GM. "Oral contraceptives. Are drug interactions of clinical significance?." Drug Saf. 1993 Jul;9: 21-37.
Publication : Drug Saf by
> Shenfield GM - Oral contraceptives. Are drug interactions of clin - 21-37

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