Acetaminophen and Ethinyl Estradiol

Effects and Recommendation :
Acetaminophen may increase blood levels of Ethinyl Estradiol. Ethinyl Estradiol may reduce or delay the effects of Acetaminophen.
Not clinically significant. No adjustments appear to be necessary.
Severity of the interaction : 1/6

Information on this interaction is found in the following publications :
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Back DJ, Orme ML. "Pharmacokinetic drug interactions with oral contraceptives." Clin Pharmacokinet. 1990 June;18: 472-84.
Publication : Clin Pharmacokinet by
> Back DJ, Orme ML - Pharmacokinetic drug interactions with oral contra - 472-84
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Minors JO, Hawood J, Birkett DJ. "Influence of sex and oral contraceptive steroids on paracetamol metabolism." Br J Clin Pharmacol. 1983 Nov;16: 503-9.
Publication : Br J Clin Pharmacol by
> Minors JO, Hawood J, Birkett DJ - Influence of sex and oral contraceptive steroids o - 503-9
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Shenfield GM. "Oral contraceptives. Are drug interactions of clinical significance?." Drug Saf. 1993 Jul;9: 21-37.
Publication : Drug Saf by
> Shenfield GM - Oral contraceptives. Are drug interactions of clin - 21-37

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