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Home : A : Acetaminophen : Acetaminophen and Isoniazid

Effects and Recommendation :
Resulting In: liver damage Liver toxicity has been reported with the use of Acetaminophen and Isoniazid.
Monitor patient closely for liver toxicity.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Epstein MM, et al. Br J Clin Pharmacol. 1991: 31:139.
Publication : Br J Clin Pharmacol by
> Epstein MM, et al - - 31:139
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Moulding TS, et al. Ann Intern Med. 1991: 114:431.
Publication : Ann Intern Med by
> Moulding TS, et al - - 114:431
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Murphy R, et al. Ann Intern Med. 1990: 113:799.
Publication : Ann Intern Med by
> Murphy R, et al - - 113:799