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Home : A : Acetaminophen : Lamotrigine and Acetaminophen

Effects and Recommendation :
Acetaminophen may reduce the serum levels and pharmacological effects of Lamotrigine.
LAMOTRIGINE dose may need to be adjusted when combined with chronic ACETAMINOPHEN use.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Depot M, et al. Clin Pharmacol Ther. 1990: 48:346.
Publication : Clin Pharmacol Ther by
> Depot M, et al - - 48:346