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Home : A : Acetaminophen : Zidovudine and Acetaminophen

Effects and Recommendation :
Concomitant use of Zidovudine and Acetaminophen may increase the risk of hepatotoxicity.
Avoid chronic dose of acetaminophen in patients while on zidovudine therapy.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Shriner K, et al. "Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine." Am J Med. 1992: 93:94-96.
Publication : Am J Med by
> Shriner K, et al - Severe hepatotoxicity in a patient receiving both - 93:94-96