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Home : C : Caffeine : Caffeine and Phenylpropanolamine HCl

Effects and Recommendation :
Phenylpropanolamine HCl may increase the serum levels and pharmacological and adverse effects of Caffeine.
Adjustment of dose may be necessary if patient exhibits signs and symptoms of CAFFEINE toxicity.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Altschuler S, et al. Int J Obes. 1982: 6:549.
Publication : Int J Obes by
> Altschuler S, et al - - 6:549
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Lake CR, et al. Am J Med. 1988: 85:339.
Publication : Am J Med by
> Lake CR, et al - - 85:339
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Lake CR, et al. Am J Med. 1989: 86:427.
Publication : Am J Med by
> Lake CR, et al - - 86:427
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Lake CR, et al. Clin Pharmacol Ther. 1990: 47:675.
Publication : Clin Pharmacol Ther by
> Lake CR, et al - - 47:675
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Noble R. DICP. 1988: 22:296.
Publication : DICP by
> Noble R - - 22:296
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Silverman HI, et al. Curr Ther Res. 1980: 28:185.
Publication : Curr Ther Res by
> Silverman HI, et al - - 28:185