Lithium and Caffeine

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Effects and Recommendation :
Caffeine may reduce serum levels of Lithium.
Advise patients that consume large amount of caffeinated products not to eliminate CAFFEINE from their diet without consulting with a physician. Monitor LITHIUM levels and adjust dose as necessary.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Jefferson JW. J Clin Psychiatry. 1988: 49:72.
Publication : J Clin Psychiatry by
> Jefferson JW - - 49:72
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Mester R, et al. Biol Psychiatry. 1995: 37:348.
Publication : Biol Psychiatry by
> Mester R, et al - - 37:348