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Home : D : Danazol : Carbamazepine and Danazol

Effects and Recommendation :
Danazol may increase the serum levels and pharmacological and adverse effects of Carbamazepine.
Avoid combination if possible. If combination is used, monitor CARBAMAZEPINE levels and observe the patient for signs of toxicity. Adjustment of CARBAMAZEPINE dose may be required when starting or stopping DANAZOL therapy.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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D'Arcy PF, et al. Int Pharm J. 1988: 2:4.
Publication : Int Pharm J by
> D'Arcy PF, et al - - 2:4
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Hayden M, et al. Med J Aust. 1991: 155:851.
Publication : Med J Aust by
> Hayden M, et al - - 155:851
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Kramer G, et al. Ther Drug Monit. 1986: 8:387.
Publication : Ther Drug Monit by
> Kramer G, et al - - 8:387
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Zielinski JJ, et al. Ther Drug Monit. 1987: 9:24.
Publication : Ther Drug Monit by
> Zielinski JJ, et al - - 9:24