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Home : D : Danazol : Danazol and Cyclosporine
Effects and Recommendation :
Resulting In: nephrotoxicity Danazol can increase the serum levels of Cyclosporine and increase the risk of toxicity.
Monitor serum bilirubin, creatinine and CYCLOSPORINE levels and adjust dose of ANDROGEN or CYCLOSPORINE as necessary.
Severity of the interaction : 3/6
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Information on this interaction is found in the following publications :
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Goffin E, et al. Nephron. 1991: 59:174.
Publication : Nephron by
> Goffin E, et al - - 59:174
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Moller BB, et al. N Engl J Med. 1985: 313:1416.
Publication : N Engl J Med by
> Moller BB, et al - - 313:1416
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Passfall J, et al. Nephrol Dial Transplant. 1994: 9:1807.
Publication : Nephrol Dial Transplant by
> Passfall J, et al - - 9:1807
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Ross WB, et al. Lancet. 1986: 1:330.
Publication : Lancet by
> Ross WB, et al - - 1:330
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