Dapsone and Didanosine

Effects and Recommendation :
Resulting In: infection Didanosine may reduce the absorption and pharmacologic effects of Dapsone.
Administer DAPSONE at least 2 hours before DIDANOSINE.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Breen GA, et al. Antimicrob Agents Chemother. 1994: 38:2227.
Publication : Antimicrob Agents Chemother by
> Breen GA, et al - - 38:2227
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Knupp CA, et al. Clin Pharmacol Ther. 1992: 51:155 .
Publication : Clin Pharmacol Ther by
> Knupp CA, et al - - 51:155
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Metroka CE, et al. N Engl J Med. 1991: 325:737.
Publication : N Engl J Med by
> Metroka CE, et al - - 325:737
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Sahai J, et al. Ann Intern Med. 1995: 123:584.
Publication : Ann Intern Med by
> Sahai J, et al - - 123:584

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