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Home : D : Dapsone : Trimethoprim and Dapsone

Effects and Recommendation :
Resulting In: Methemoglobinemia Concomitant administartion of Dapsone and Trimethoprim may cause toxicity of both agents. Effects of Dapsone and Trimethoprim may be increased.
Monitor patients for DAPSONE toxicity-methemoglobin levels.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Lee BL, et al. Ann Intern Med. 1989: 110:606.
Publication : Ann Intern Med by
> Lee BL, et al - - 110:606