Felbamate and Phenobarbital

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Home : F : Felbamate : Felbamate and Phenobarbital

Effects and Recommendation :
Felbamate can increase the serum levels of Phenobarbital and increase the risk of toxicity.
Monitor PHENOBARBITAL level and patient response. Adjust dose of either drugs as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Gidal BE, et al. Ann Pharmacother. 1994: 28:455.
Publication : Ann Pharmacother by
> Gidal BE, et al - - 28:455
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Reidenberg P, et al. Clin Pharmacol Ther. 1995: 58:279.
Publication : Clin Pharmacol Ther by
> Reidenberg P, et al - - 58:279