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Home : F : Fentanyl : Amiodarone HCl and Fentanyl
Effects and Recommendation :
Resulting In: Hypotension, Sinus arrest, bradycardia Combining Amiodarone HCl and Fentanyl can result in bradycardia, sinus arrest and hypotension.
Monitor hemodynamic function, and administer inotropic, chronotropic, and pressor support as indicated. The bradycardia is usually unresponsive to atropine. Large doses of Vasopressors eg. Epinephrine have been used.
Severity of the interaction : 5/6
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Information on this interaction is found in the following publications :
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Gallagher JD, et al. Anesthesiology. 1981: 55:186.
Publication : Anesthesiology by
> Gallagher JD, et al - - 55:186
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Koblin DD, et al. Anesthesiology. 1987: 66:551.
Publication : Anesthesiology by
> Koblin DD, et al - - 66:551
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Liberman BA, et al. Can Anaesth Soc J. 1985: 32:629.
Publication : Can Anaesth Soc J by
> Liberman BA, et al - - 32:629
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MacKinnon G, et al. Can J Surg. 1983: 26:355.
Publication : Can J Surg by
> MacKinnon G, et al - - 26:355
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Navalgund AA, et al. Anesth Analg. 1986: 65:414.
Publication : Anesth Analg by
> Navalgund AA, et al - - 65:414
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