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Home : F : Ferrous Fumarate : Ferrous Fumarate and Aluminum Hydroxide

Effects and Recommendation :
Gastrointestinal absorption of Iron may be reduced by concommitant administration of Aluminum Hydroxide.
Separate administration if IRON and ANTACIDS by at least 2 hours if possible.
Severity of the interaction : 1/6

Information on this interaction is found in the following publications :
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Corby DG, McCullen AH, Chadwick EW, et al. "Effects of orally administered magnesium hydroxide in experimental iron intoxication." J Toxicol Clin Toxicol. 1985-86: 23:489-99.
Publication : J Toxicol Clin Toxicol by
> Corby DG, McCullen AH, Chadwick EW, et al - Effects of orally administered magnesium hydroxide - 23:489-99
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O'Neil-Cutting MA, Crosby WH. "The effect of antacids on the absorption of simultaneously ingested iron." JAMA. 1986: 255:1468-70.
Publication : JAMA by
> O'Neil-Cutting MA, Crosby WH - The effect of antacids on the absorption of simult - 255:1468-70
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Wallace KL, Curry SC, LoVecchio F, et al. "Effect of magnesium hydroxide on iron absorption after ferrous sulfate." Am J Emerg Med. 1999 Nov;34: 685-7.
Publication : Am J Emerg Med by
> Wallace KL, Curry SC, LoVecchio F, et al - Effect of magnesium hydroxide on iron absorption a - 685-7