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Home : G : Gemfibrozil : Rosiglitazone and Gemfibrozil

Effects and Recommendation :
Resulting In: hypoglycemia Gemfibrozil may inhibit the metabolism and increase the serum concentration of Rosiglitazone.
If combination is needed, monitor blood glucose closely and lower dose of Avandia if needed by 50-70%. Fenofibrate may be a better option.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Jellin JM, Gregory P, Bartz F, Hitchens K et al. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database 3rd ed. Stockton CA: Therapeutic Research Faculty, 2003.
Publication : Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database 3rd ed by Jellin JM, Gregory P, Bartz F, Hitchens K et al
> Jellin JM, Gregory P, Bartz F, Hitchens K et al - -