Haloperidol and Fluoxetine

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Effects and Recommendation :
Combination of Haloperidol and Fluoxetine has been associated with severe extrapyramidal reactions.
Observe patients for signs of extrapyramidal symptoms and discontinue one or the other of these medications if interactions occurs.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Goff DC, et al. Am J Psychiatry. 1991: 148:790.
Publication : Am J Psychiatry by
> Goff DC, et al - - 148:790
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Tate JL. Am J Psychiatry. 1989: 146:399.
Publication : Am J Psychiatry by
> Tate JL - - 146:399