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Home : H : Haloperidol : Haloperidol and Methyldopa

Effects and Recommendation :
Resulting In: Psychosis, extrapyramidal effects Methyldopa may increase or decrease effectivness of Haloperidol.
Depending on patient response, adjust therapy as needed. Also consider using alternative therapy.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Chouinard G, et al. Curr Ther Res. 1973: 15:473.
Publication : Curr Ther Res by
> Chouinard G, et al - - 15:473
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Nadel I, et al. Br J Psychiatry. 1979: 135:484.
Publication : Br J Psychiatry by
> Nadel I, et al - - 135:484
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Thornton WE. N Engl J Med. 1976: 294:1222.
Publication : N Engl J Med by
> Thornton WE - - 294:1222