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Home : H : Haloperidol : Lithium and Haloperidol

Effects and Recommendation :
Resulting In: Extrapyramidal disorder, Fever, Leukocytosis, Encephalopathy Concomitant use of Lithium and Haloperidol can potentiate some adverse effects.
Use this combination with extreme caution. Monitor patients neurologic function closely and discontinue one drug or the other if symptoms occur.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Addonizio G. J Clin Psychopharmacol. 1985: 5:296.
Publication : J Clin Psychopharmacol by
> Addonizio G - - 5:296
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Bastrup, PC et al. JAMA. 1976: 236:2645.
Publication : JAMA by
> Bastrup, PC et al - - 236:2645
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Biederman J, et al. Arch Gen Psychiatry. 1979: 36:327.
Publication : Arch Gen Psychiatry by
> Biederman J, et al - - 36:327
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Cohen WJ, et al. JAMA. 1974: 230:1283.
Publication : JAMA by
> Cohen WJ, et al - - 230:1283
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Gibb WRG, et al. Quart J Med. 1985: 56:421.
Publication : Quart J Med by
> Gibb WRG, et al - - 56:421
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Goldney RD, et al. Am J Psychiatry. 1986: 143:882.
Publication : Am J Psychiatry by
> Goldney RD, et al - - 143:882
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Jeffries J, et al. Can J Psychiatry. 1984: 29:601.
Publication : Can J Psychiatry by
> Jeffries J, et al - - 29:601
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Juhl RP, et al. Dis Nerv Syst. 1977: 38:675.
Publication : Dis Nerv Syst by
> Juhl RP, et al - - 38:675
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Keitner GI, et al. J Clin Psychopharmacol. 1984: 4:104.
Publication : J Clin Psychopharmacol by
> Keitner GI, et al - - 4:104
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Loudon JB, et al. Lancet. 1976: 2:1088.
Publication : Lancet by
> Loudon JB, et al - - 2:1088
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Miller F, et al. Hosp Comm Psychiatry. 1987: 38:1219.
Publication : Hosp Comm Psychiatry by
> Miller F, et al - - 38:1219
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Prakash R, et al. Compr Psychiatry. 1982: 23:567.
Publication : Compr Psychiatry by
> Prakash R, et al - - 23:567
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Sandyk R, et al. S Afr Med J. 1983: 64:875.
Publication : S Afr Med J by
> Sandyk R, et al - - 64:875
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Saran A, et al. Neuropsychobiology. 1988: 20:152.
Publication : Neuropsychobiology by
> Saran A, et al - - 20:152
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Spring G, et al. Am J Psychiatry. 1981: 138:818.
Publication : Am J Psychiatry by
> Spring G, et al - - 138:818
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Thomas C, et al. Lancet. 1982: 1:626.
Publication : Lancet by
> Thomas C, et al - - 1:626
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Thomas CJ. Br J Clin Psychiatry. 1979: 134:552.
Publication : Br J Clin Psychiatry by
> Thomas CJ - - 134:552
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Thornton WE, et al. Can Psychiatr Assoc J. 1975: 20:281.
Publication : Can Psychiatr Assoc J by
> Thornton WE, et al - - 20:281