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Home : I : Ibutilide Fumarate : Cisapride and Ibutilide Fumarate

Effects and Recommendation :
Torsades de pointes Use of Ibutilide Fumarate with Cisapride may increase the risk of life-threatening cardiac arrhythmias, including torsades de pointes.
CISAPRIDE is contraindicated in GROUP I and GROUP III ANTIARRHYTHMIC agents.
Severity of the interaction : 6/6

Information on this interaction is found in the following publications :
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Kuroda T, et al. Pharmacobiodyn. 1992: 15:395.
Publication : Pharmacobiodyn by
> Kuroda T, et al - - 15:395
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Thomas M, et al. Br J Clin Pharmacol. 1996: 41:77.
Publication : Br J Clin Pharmacol by
> Thomas M, et al - - 41:77