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Home : I : Ibutilide Fumarate : Grepafloxacin and Ibutilide Fumarate

Effects and Recommendation :
Torsades de pointes Use of Ibutilide Fumarate with Grepafloxacin may increase the risk of life-threatening cardiac arrhythmias, including torsades de pointes.
GREPAFLOXACIN is contraindicated in patients receiving GROUP Ia and GROUP III ANTIARRHYTHMICS.
Severity of the interaction : 6/6

Information on this interaction is found in the following publications :
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Product Information. Grepafloxacin (Raxar). Glaxo Wellcome, November 1997.
Publication : Grepafloxacin (Raxar) by Product Information
> Product Information - -
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Thomas M, et al. Br J Clin Pharmacol. 1996: 41:77.
Publication : Br J Clin Pharmacol by
> Thomas M, et al - - 41:77