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Home : I : Imipenem : Cyclosporine and Imipenem

Effects and Recommendation :
Resulting In: CNS side effects Concomitant administartion of Cyclosporine and Imipenem may cause toxicity of both agents.
Consider using an alternative antibiotics. Monitor for additive CNS side effects.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Bosmuller C, et al. Nephron. 1991: 58:362.
Publication : Nephron by
> Bosmuller C, et al - - 58:362
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Zazgornik J, et al. Clin Nephrol. 1986: 26:265.
Publication : Clin Nephrol by
> Zazgornik J, et al - - 26:265