Omeprazole and Indinavir

Home - Foreign Pharmacy List - Help - Link Exchange - Contact

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Home : I : Indinavir : Omeprazole and Indinavir

Effects and Recommendation :
Gastrointestinal absorption of Indinavir may be reduced by concommitant administration of Omeprazole.
Monitor patients for a decrease in antiviral activity and adjust the dose of Indinavir as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
----------
Burger DM, Hugen PW, Kroon FP, et al. "Pharmacokinetic interaction between the proton pump inhibitor omeprazole and the HIV protease inhibitor indinavir." AIDS. 1998 Oct 22;12: 2080-2.
Publication : AIDS by
> Burger DM, Hugen PW, Kroon FP, et al - Pharmacokinetic interaction between the proton pum - 2080-2