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Home : I : Indomethacin : Phenylpropanolamine HCl and Indomethacin

Effects and Recommendation :
Resulting In: High blood pressure Concomitant use of Indomethacin and Phenylpropanolamine HCl can potentiate some adverse effects.
Avoid this combination if possible. Monitor blood pressure. If hypertension occurs, discontinue both drugs.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Lee KY, et al. Lancet. 1979: 1:1110.
Publication : Lancet by
> Lee KY, et al - - 1:1110
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McKenney JM, et al. DICP. 1991: 25:234.
Publication : DICP by
> McKenney JM, et al - - 25:234
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Sauls LJ. N Engl J Med. 1969: 280:1363.
Publication : N Engl J Med by
> Sauls LJ - - 280:1363
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Shapiro SR. N Engl J Med. 1969: 280:1363.
Publication : N Engl J Med by
> Shapiro SR - - 280:1363