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Home : K : Ketoconazole : Betamethasone Sodium Phosphate and Ketoconazole

Effects and Recommendation :
Azole antifungals may enhance the pharmacological and toxic effects of Corticosteroids.
Monitor patient for adverse effects and reduce CORTICOSTEROIDS as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Glynn AM, et al. Clin Pharmacol Ther. 1986: 39:654.
Publication : Clin Pharmacol Ther by
> Glynn AM, et al - - 39:654
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Jusko WJ. Clin Pharmacol Ther. 1990: 47:418.
Publication : Clin Pharmacol Ther by
> Jusko WJ - - 47:418
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Kandrotas RJ, et al. Clin Pharmacol Ther. 1987: 42:465.
Publication : Clin Pharmacol Ther by
> Kandrotas RJ, et al - - 42:465
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Yamashita SK, et al. Clin Pharmacol Ther. 1991: 49:558.
Publication : Clin Pharmacol Ther by
> Yamashita SK, et al - - 49:558
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Zürcher RM, et al. Clin Pharmacol Ther. 1989: 45:366.
Publication : Clin Pharmacol Ther by
> Zürcher RM, et al - - 45:366
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Zürcher RM, et al. Clin Pharmacol Ther. 1990: 47:419.
Publication : Clin Pharmacol Ther by
> Zürcher RM, et al - - 47:419