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Home : K : Ketoconazole : Pioglitazone HCl and Ketoconazole

Effects and Recommendation :
Ketoconazole may inhibit the metabolism of Pioglitazone HCl thus increasing the serum concentration of Pioglitazone HCl.
Monitor patient for loss of blood sugar control . May need a lower PIOGLITAZONE dose if indicated.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Product Information. Pioglitazone HCL (Actos). Lilly, July 1999.
Publication : Pioglitazone HCL (Actos) by Product Information
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