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Home : L : Leflunomide : Leflunomide and Methotrexate Sodium

Effects and Recommendation :
Resulting In: abnormal liver function tests Leflunomide may increase the risk of liver toxicity from Methotrexate.
Monitor liver functions. Elevations of liver enzymes usually resolve after disconitnuation of LEFLUNOMIDE.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Product Information. Leflunomide (Arava). Hoechst Marion Russel, September 1998.
Publication : Leflunomide (Arava) by Product Information
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