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Home : L : Levamisole HCl : Levamisole HCl and Fluorouracil
Effects and Recommendation :
Resulting In: Hepatotoxicity Concomitant use of Levamisole HCl and Fluorouracil may increase the risk of hepatotoxicity.
Monitor patients for mild and usually asymptomatic hepatotoxocity, specifically, increased alkaline phosphatase, serum transaminases, or serum bilirubin
Severity of the interaction : 3/6
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Information on this interaction is found in the following publications :
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Moertel CG, Fleming TR, Macdonald JS, et al. "Hepatic toxicity associated with fluorouracil plus levamisole adjuvant therapy.." J Clin Oncol. 1993 Dec;11: 2386-90.
Publication : J Clin Oncol by
> Moertel CG, Fleming TR, Macdonald JS, et al - Hepatic toxicity associated with fluorouracil plus - 2386-90
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