Guanethidine Monosulfate and Maprotiline HCl

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Home : M : Maprotiline HCl : Guanethidine Monosulfate and Maprotiline HCl

Effects and Recommendation :
Resulting In: Hypertension Maprotiline HCl can reverse the pharmacological effects of Guanethidine Monosulfate.
Monitor blood pressure. Increase the dose of GUANETHIDINE or discontinue MAPROTILINE if hypertension develops.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Briant RH, et al. Br J Clin Pharmacol. 1974: 1:113.
Publication : Br J Clin Pharmacol by
> Briant RH, et al - - 1:113
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Smith AJ, et al. J Int Med Res. 1975: 3(Suppl 2):55.
Publication : J Int Med Res by
> Smith AJ, et al - - 3(Suppl 2):55