Levodopa and Papaverine

Effects and Recommendation :
Resulting In: worsening of Parkinsonian symptoms Papaverine may reduce the Antiparkinson's effects of Levodopa.
Avoid this combination if possible.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
----------
Duvoisin RC. JAMA. 1975: 231:845.
Publication : JAMA by
> Duvoisin RC - - 231:845
----------
Gardos G, et al. N Engl J Med. 1975: 292:1355.
Publication : N Engl J Med by
> Gardos G, et al - - 292:1355
----------
Montastruc JL, et al. Ann Neurol. 1987: 22:558.
Publication : Ann Neurol by
> Montastruc JL, et al - - 22:558
----------
Posner DM. JAMA. 1975: 233:768.
Publication : JAMA by
> Posner DM - - 233:768

Home : P : Papaverine : Levodopa and Papaverine