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Home : Q : Quinidine : Codeine and Quinidine

Effects and Recommendation :
Quinidine may reduce the analgesic effects of Codeine.
Observe the patient's response to CODEINE. Consider an alternative analgesics if necessary.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Caraco Y, et al. J Pharmacol Exp Ther. 1996: 278:1165.
Publication : J Pharmacol Exp Ther by
> Caraco Y, et al - - 278:1165
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Desmeules J, et al. Clin Pharmacol Ther. 1989: 45:122 .
Publication : Clin Pharmacol Ther by
> Desmeules J, et al - - 45:122
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Sindrup SH, et al. Clin Pharmacol Ther. 1990: 48:686.
Publication : Clin Pharmacol Ther by
> Sindrup SH, et al - - 48:686
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Sindrup SH, et al. Eur J Clin Pharmacol. 1992: 42:587.
Publication : Eur J Clin Pharmacol by
> Sindrup SH, et al - - 42:587
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Sindrup SH, et al. Eur J Clin Pharmacol. 1996: 49:503.
Publication : Eur J Clin Pharmacol by
> Sindrup SH, et al - - 49:503