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Home : Q : Quinidine : Dextromethorphan HBr and Quinidine

Effects and Recommendation :
Resulting In: Fatigue, Insomnia, Dizziness, confusion, nervousness, shortness of breath Quinidine may increase the serum levels and pharmacological and adverse effects of Dextromethorphan HBr.
Monitor for DEXTROMETHORPHAN side effects and reduce dose as needed.
Severity of the interaction : 1/6

Information on this interaction is found in the following publications :
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Schadel M, et al. J Clin Psychopharmacol. 1995: 15:263.
Publication : J Clin Psychopharmacol by
> Schadel M, et al - - 15:263
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Zhang Y, et al. Clin Pharmacol Ther. 1992: 51:647.
Publication : Clin Pharmacol Ther by
> Zhang Y, et al - - 51:647