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Home : Q : Quinidine : Digitoxin and Quinidine
Effects and Recommendation :
Quinidine may enhance the pharmacological and toxic effects of Digitoxin. Quinidine may increase blood levels of Digitoxin.
When taking this drug combination, reduce the dose of DIGITOXIN by 30-70%. Monitor DIGITOXIN level and watch for signs of toxicity.
Severity of the interaction : 5/6
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Information on this interaction is found in the following publications :
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Fenster PE, et al. Ann Intern Med. 1980: 93:698.
Publication : Ann Intern Med by
> Fenster PE, et al - - 93:698
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Garty M, et al. Ann Intern Med. 1981: 94:35.
Publication : Ann Intern Med by
> Garty M, et al - - 94:35
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Kuhlmann J, et al. Clin Pharmacol Ther. 1986: 39:288.
Publication : Clin Pharmacol Ther by
> Kuhlmann J, et al - - 39:288
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Ochs HR, et al. N Engl J Med. 1980: 303:672.
Publication : N Engl J Med by
> Ochs HR, et al - - 303:672
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