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Home : Q : Quinidine : Quinidine and Amiodarone HCl

Effects and Recommendation :
Resulting In: Hypotension, Arrhythmias, Vertigo, gastrointestinal distress Amiodarone HCl can increase the serum levels of Quinidine and increase the risk of toxicity.
Avoid this drug combination if possible. Monitor QUINIDINE level and toxicity. Adjust QUINIDINE dosage as needed.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Kerin NZ, et al. Am Heart J. 1983: 125:1017.
Publication : Am Heart J by
> Kerin NZ, et al - - 125:1017
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Saal AK, et al. Am J Cardiol. 1984: 53:1264.
Publication : Am J Cardiol by
> Saal AK, et al - - 53:1264
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Tartini R, et al. Lancet. 1982: 1:1327.
Publication : Lancet by
> Tartini R, et al - - 1:1327