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Home : Q : Quinidine : Quinidine and Phenytoin Sodium, Prompt

Effects and Recommendation :
Phenytoin may reduce the pharmacologic effects of Quinidine.
Monitor QUINIDINE level and increase QUINIDINE dose as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Data JL, et al. N Engl J Med. 1976: 294:699.
Publication : N Engl J Med by
> Data JL, et al - - 294:699
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Farringer JA, et al. Drug Intell Clin Pharm. 1985: 19:461.
Publication : Drug Intell Clin Pharm by
> Farringer JA, et al - - 19:461
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Jaillon P, et al. J Pharmacol Exp Ther. 1980: 213:33.
Publication : J Pharmacol Exp Ther by
> Jaillon P, et al - - 213:33
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Kroboth FJ, et al. N Engl J Med. 1983: 308:725.
Publication : N Engl J Med by
> Kroboth FJ, et al - - 308:725
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Rogers GC, et al. DICP. 1983: 17:819.
Publication : DICP by
> Rogers GC, et al - - 17:819
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Urbano AM. N Engl J Med. 1983: 308:725.
Publication : N Engl J Med by
> Urbano AM - - 308:725