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Home : R : Ramipril : Ramipril and Aspirin

Effects and Recommendation :
Aspirin can reduce the effectivness of Ramipril.
If aspirin is needed to prevent heart attack or stroke, then low dose is needed (81mg/d)
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Hall D, et al. J Am Coll Cardiol. 1992: 20:1549.
Publication : J Am Coll Cardiol by
> Hall D, et al - - 20:1549
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Nawarskas JJ, et al. Pharmacotherapy. 1998: 18:1041.
Publication : Pharmacotherapy by
> Nawarskas JJ, et al - - 18:1041
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Nawarskas JJ, Spinler SA.. "Update on the interaction between aspirin and ACE inhibitors." Pharmacotherapy. 2000 June: (6):698-710.
Publication : Pharmacotherapy by
> Nawarskas JJ, Spinler SA. - Update on the interaction between aspirin and ACE - (6):698-710