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Home : T : Tacrolimus : Tacrolimus and Chloramphenicol

Effects and Recommendation :
Resulting In: nephrotoxicity Chloramphenicol may increase the serum levels of Tacrolimus and increase the risk of toxicity.
Monitor TACROLIMUS level and renal function; adjust dosage when starting or stopping CHLORAMPHENICOL.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Schulman SL, et al. Transplantation. 1998: 65:1397.
Publication : Transplantation by
> Schulman SL, et al - - 65:1397