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Home : T : Tacrolimus : Tacrolimus and Danazol

Effects and Recommendation :
Resulting In: nephrotoxicity Danazol may increase the serum levels of Tacrolimus and increase the risk of toxicity.
Monitor TACROLIMUS level and renal function; adjust TACROLIMUS dosage as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Shapiro R, et al.. Lancet. 1993: 341:1344.
Publication : Lancet by
> Shapiro R, et al. - - 341:1344