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Home : V : Vasopressin : Vasopressin and Adenosine

Effects and Recommendation :
Vasopressin and Adenosine may have additive effects on QT prolongation
It is not recommended to administer concurrent drugs that both prolong QTc interval.
Severity of the interaction : 5/6

Information on this interaction is found in the following publications :
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Harrington GR, Froelich EG. "Adenosine-induced torsades de pointes." Chest. Apr 1993: 103(4):1299-301.
Publication : Chest by
> Harrington GR, Froelich EG - Adenosine-induced torsades de pointes - 103(4):1299-301
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Mauro VF, Bingle JF, Ginn SM, Jafri FM. "Torsade de pointes in a patient receiving intravenous vasopressin.." Crit Care Med. Feb 1988: 16(2):200-1.
Publication : Crit Care Med by
> Mauro VF, Bingle JF, Ginn SM, Jafri FM - Torsade de pointes in a patient receiving intraven - 16(2):200-1