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Home : W : Warfarin Sodium : Ethacrynic Acid and Warfarin Sodium

Effects and Recommendation :
Ethacrynic Acid may increase the anticoagulant effects of Warfarin Sodium.
Monitor anticoagulant activity. A lower dose of ANTICOAGULANT may be required.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Nilsson CM, et al. J Clin Pharmacol. 1978: 18:91.
Publication : J Clin Pharmacol by
> Nilsson CM, et al - - 18:91
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Nipper H, et al. J Clin Pharmacol. 1981: 21:654.
Publication : J Clin Pharmacol by
> Nipper H, et al - - 21:654
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Ogiso T, et al. J Pharm Dyn. 1982: 5:829.
Publication : J Pharm Dyn by
> Ogiso T, et al - - 5:829
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Petrick RJ, et al. JAMA. 1975: 231:843.
Publication : JAMA by
> Petrick RJ, et al - - 231:843
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Sellers EM, et al. Clin Pharmacol Ther. 1970: 11:524.
Publication : Clin Pharmacol Ther by
> Sellers EM, et al - - 11:524