Isoniazid and Warfarin Sodium

Effects and Recommendation :
Resulting In: increased bleeding tendencies Isoniazid may increase the anticoagulant effects of Warfarin Sodium.
Monitor prothrombin time and adjust WARFARIN dose as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Almog S, et al. South Med J. 1988: 81:1304.
Publication : South Med J by
> Almog S, et al - - 81:1304
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Eade NR, et al. Am Rev Respir Dis. 1971: 103:792.
Publication : Am Rev Respir Dis by
> Eade NR, et al - - 103:792
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Kiblawi SS, et al. Clin Ther. 1979: 2:235.
Publication : Clin Ther by
> Kiblawi SS, et al - - 2:235
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Rosenthal AR, et al. JAMA. 1977: 238:2177.
Publication : JAMA by
> Rosenthal AR, et al - - 238:2177

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