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Home : W : Warfarin Sodium : Omeprazole and Warfarin Sodium

Effects and Recommendation :
Omeprazole can increase the anticoagulant effects of Warfarin Sodium.
Monitor anticoagulation factors when adding or discontinuing WARFARIN. Adjust WARFARIN dose as needed.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Ahmad S. "Omeprazole-warfarin interaction." South Med J. 1991: 84:674.
Publication : South Med J by
> Ahmad S - Omeprazole-warfarin interaction - 84:674
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Sutfin T, et al. Ther Drug Monit. 1989: 11:176.
Publication : Ther Drug Monit by
> Sutfin T, et al - - 11:176
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Unge P, et al. "A study of the interaction of omeprazole and warfarin in anticoagulated patients." Br J Clin Pharmacol. 1992: 34:509.
Publication : Br J Clin Pharmacol by
> Unge P, et al - A study of the interaction of omeprazole and warfa - 34:509