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Home : Z : Zidovudine : Zidovudine and Acyclovir

Effects and Recommendation :
Resulting In: neurotoxicity Concomitant use of Acyclovir and Zidovudine (AZT) may cause severe drowsiness and lethargy.
Warn patients about extreme fatigue. Bed rest may be needed.
Severity of the interaction : 1/6

Information on this interaction is found in the following publications :
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Bach MC. N Engl J Med. 1987: 316:547.
Publication : N Engl J Med by
> Bach MC - - 316:547