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Home : Z : Zidovudine : Zidovudine and Atovaquone

Effects and Recommendation :
Atovaquone can increase the serum levels of Zidovudine (AZT) and increase the risk of toxicity.
Monitor the efects of ZIDOVUDINE, may need to decrease its dosage.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Lee BL, et al. "Atovaquone inhibits the glucuronidation and increases the plasma concentrations of zidovudine." Clin Pharmacol Ther. 1996: 59:14-21.
Publication : Clin Pharmacol Ther by
> Lee BL, et al - Atovaquone inhibits the glucuronidation and increa - 59:14-21