Zidovudine and Interferon Beta-1A

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Effects and Recommendation :
Interferon Beta-1A can increase the serum levels of Zidovudine and increase the risk of toxicity.
Monitor patient response; may need to lower the dose of ZIDOVUDINE.
Severity of the interaction : 3/6

Information on this interaction is found in the following publications :
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Nokta M, Loh JP, Douidar SM, et al.. "Metabolic interaction of recombinant interferon-beta and zidovudine in AIDS patients (Abstract)." J Interferon Res. 1991: 159-64.
Publication : J Interferon Res by Nokta M
> Nokta M, Loh JP, Douidar SM, et al. - Metabolic interaction of recombinant interferon-be - 159-64